L-Glutathione, reduced
Glutathione (GSH) is a tripeptide (?-glutamylcysteinylglycine) widely distributed in both plants and animals.{1813,4672} GSH serves as a nucleophilic co-substrate to glutathione transferases in the detoxification of xenobiotics and is an essential electron donor to glutathione peroxidases in the reduction of hydroperoxides.{4672,165} GSH is also involved in amino acid transport and maintenance of protein sulfhydryl reduction status.{4669,4670} The concentration of GSH ranges from a few micromolar in plasma to several millimolar in tissues such as liver.
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