HumanKine recombinant human TGF beta 2 protein
Transforming growth factor beta-2 (TGFB2) belongs to the TGF-beta family. TGFB2 is a secreted protein known as a cytokine that plays a vital role during embryonic development (PMID 19289080). TGFB2 regulates cell proliferation, differentiation, adhesion, migration by transducing the signal through transmembrane receptors type I and type II (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins (PMID 18313409). Disruption of the TGFB/SMAD pathway has been implicated in many cancers types. TGFB2 has suppressive effects on interleukin-2 dependent T-cell growth (PMID 12064833). The TGF?2 protein plays a role in the blood vessels formation, the regulation of muscle tissue and body fat development. TGF?-2 is especially abundant in tissues related to the skeleton, where it helps regulate bone growth and form the extracellular matrix in the spaces between cells.
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HumanKine recombinant human TGF beta 2 protein
HZ-1092-100ug
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HumanKine recombinant human TGF beta 2 protein
HZ-1092-100ug
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